Peng-Ye Wang

Professor of Physics, Ph.D.
Director of the Laboratory of Soft Matter Physics

　
( Group ) 　
　 　
　 　
　 　

 

Corresponding address:

  

  Institute of Physics, Chinese Academy of Sciences (CAS)

  P.O. Box 603, Beijing 100080, China

  Tel:

86-10-82649569 (or 8)

  Fax:

86-10-82649531, 86-10-82640224

  E-mail:

pywang@aphy.iphy.ac.cn

 

Education:

 

  1978-1982

Student in Shandong University, B.S.(1982)

  1982-1988

Graduate student in Institute of Physics, CAS, M.S.(1985), Ph.D.(1988)

 

Research experience:

 

　

  1988-1989

Assistant researcher in Institute of Physics, CAS

  1989-1991

Postdoc in Istituto Nazionale di Ottica, Firenze, Italy

  1991-1992

Associate researcher of CNRS in Laboratoire de Spectroscopie Hertzienne, Universite des Sciences et Technologies de Lille, France

  1992 -

Researcher in Institute of Physics, CAS

  1998-1999

Visiting scholar in Optics and Fluid Dynamics Department, Risø National Laboratory, Denmark

  1999-2000

Visiting scholar in Department of Physics, Heriot-Watt University, UK, as a Research Fellow of the Royal Society of London

  2006.5-8

Visiting scholar in Stanford University (Steven Chu group), USA

 

Current research interests:

 

  Interactions between DNA and proteins such as histones

  Dynamics of bio-molecular motors

  Brownian dynamics and molecular dynamics simulations of bio-macromolecules

 

Main achievements:

 

  Published over 100 scientific papers

  Won the fourth award of the National Natural Science Prize of China

  Won the second award of the Science and Technology Advance Prize of CAS

  Obtained the National Science Fund for Distinguished Young Scholars

 

Selected publications:

　

  1. “Brownian dynamics simulation of the effect of histone modification on nucleosome structure”

Wei Li, Shuo-Xing Dou, Ping Xie, and Peng-Ye Wang

Phys. Rev. E 75, 051915 (2007).

  1.  “The arginine finger of the Bloom syndrome protein: its structural organization and its role in energy coupling”

Hua Ren, Shuo-Xing Dou, Pascal Rigolet, Ye Yang, Peng-Ye Wang, Mounira Amor-Gueret and Xu Guang Xi

Nucleic Acids Research, 35, 6029–6041 (2007).

  1.  “Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein”

Rong-Bing Guo, Pascal Rigolet, Hua Ren, Bo Zhang, Xing-Dong Zhang, Shuo-Xing Dou, Peng-Ye Wang, Mounira Amor-Gueret and Xu Guang Xi

Nucleic Acids Research, 35, 6297–6310 (2007).

  1.  “Study the effects of divalent metallic ions on the combination of DNA and histones with fluorescence anisotropy assays”

LIU YuYing, WANG PengYe, DOU ShuoXing, XIE Ping, XI XuGuang

Chinese Science Bulletin, 52, 1166-1171 (2007).

  1. “Processivity of single-headed kinesin motors”

Ping Xie, Shuo-Xing Dou and Peng-Ye Wang

Biochimica et Biophysica Acta 1767, 1418–1427 (2007).

  1.  “Limping of Homodimeric Kinesin Motors”

Ping Xie, Shuo-Xing Dou and Peng-Ye Wang

J. Mol. Biol. 366, 976–985 (2007).

  1.  “Brownian dynamics simulation of directional sliding of histone octamers caused by DNA bending”

Wei Li, Shuo-Xing Dou, Ping Xie, Peng-Ye Wang

Phys. Rev. E 73, 051909 (2006).

  1.  “Model for kinetics of wild-type and mutant kinesins”

Ping Xie, Shuo-Xing Dou, Peng-Ye Wang

BioSystems 84, 24 (2006).

  1. “Manipulating DNA molecules in nanofluidic channels”

Kai-Ge Wang, Shuanglin Yue, Lei Wang, Aizi Jin, Changzhi Gu, Peng-Ye Wang, Yuchun Feng, Yuncheng Wang, Hanben Niu

Microfluid Nanofluid 2, 85 (2006).

  1.  “A hand-over-hand diffusing model for myosin-VI molecular motors”

Ping Xie, Shuo-Xing Dou, Peng-Ye Wang

Biophysical Chemistry 122, 90 (2006).

  1. “E. coli RecQ is a rapid, efficient and monomeric helicase”

Xing-Dong Zhang, Shuo-Xing Dou, Ping Xie, Jin-Shan Hu, Peng-Ye Wang, Xu Guang Xi

J. Biol. Chem. 281, 12655 (2006).

  1. “Mechanochemical couplings of kinesin motors”

Ping Xie, Shuo-Xing Dou, Peng-Ye Wang

Biophysical Chemistry 123, 58 (2006).

  1. “A model for biased diffusion of collagenase along collagen fibrils”

Jun Qian, Ping Xie, Shuo-Xing Dou, Peng-Ye Wang

J. Theor. Biol. 243, 322 (2006).

  1.  “The histone octamer influences the wrapping direction of DNA on it: Brownian dynamics simulation of the nucleosome chirality”

Wei Li, Shuo-Xing Dou, Peng-Ye Wang

J. Theor. Biol. 235, 365 (2005).

  1. “RecQ Helicase-catalyzed DNA Unwinding Detected by Fluorescence Resonance Energy Transfer”

Xing-Dong ZHANG, Shuo-Xing DOU, Ping XIE, Peng-Ye WANG, Xu Guang XI

Acta Biochimica et Biophysica Sinica 37, 593 (2005).

  1. “A model for processivity of molecular motors”

Ping Xie, Shuo-Xing Dou, and Peng-Ye Wang

Chin. Phys. 13, 1569 (2004).

  1. “Brownian dynamics simulation of nucleosome formation and disruption under stretching”

Wei Li, Shuo-Xing Dou, Peng-Ye Wang

J. Theor. Biol. 230, 375-383 (2004).

  1. “Ionic effect on combing of single DNA molecules and observation of their force-induced melting by fluorescence microscopy”

Yu-Ying Liu, Peng-Ye Wang, Shuo-Xing Dou, Wei-Chi Wang, Ping Xie, Hua-Wei Yin, Xing-Dong Zhang, Xu Guang Xi

J. Chem. Phys. 121, 4302-4309 (2004).

  1. “The Zinc Finger Motif of Escherichia coli RecQ Is Implicated in Both DNA Binding and Protein Folding”

Jie Lin Liu, Pascal Rigolet, Shuo-Xing Dou, Peng-Ye Wang, and Xu Guang Xi

J. Biol. Chem. 279,  42794-42802 (2004).

  1. “The DNA Binding Properties of the Escherichia coli RecQ Helicase”

Shuo-Xing Dou, Peng-Ye Wang, Hou Qiang Xu, and Xu Guang Xi

J. Biol. Chem. 279,  6354-6363 (2004).[ Abstract ]

  1.  “Control of spiral waves and turbulent states in a cardiac model by travelling-wave perturbations”

Peng-Ye Wang, Ping Xie, and Hua-Wei Yin

Chin. Phys. 12, 674 (2003). [ PDF ( 258kB ) ]

  1.  “Interactions between DNA and histones - a dynamic process of nucleosome formation”

Wei Li, Peng-Ye Wang, Shuo-Xing Dou, and Pei-Qing Tong

Chin. Phys. 12, 226 (2003). [ PDF ( 258kB ) ], [ PS(WinZip) ( 365kB ) ], [PS ( 6.7GB ) ]

  1.  “Excitability and pattern formation in a liquid crystal Fabry-Pérot interferometer”

Peng-Ye Wang, Weiping Lu, Dejin Yu, and R.G. Harrison

Opt. Commun. 189, 127 (2001). [ PDF ( 402kB ) ]

  1. “Eliminating spatiotemporal chaos and spiral waves by weak spatial perturbations”

Peng-Ye Wang and Ping Xie

Phys. Rev. E 61, 5120 (2000). [ PDF ( 292kB ) ]

  1.  “Selecting optical patterns with spatial phase modulation”

Peng-Ye Wang and M. Saffman

Opt. Lett. 24, 1118 (1999). [ PDF ( 643kB ) ]

  1.  “Bifurcations of hexagonal patterns stabilized and selected with spatial perturbations in a wide-aperture laser”

R. Meucci, A. Labate, M. Ciofini, and Peng-Ye Wang

Quantum Semiclass. Opt. 10, 803 (1998). [ PDF ( 131kB ) ]

  1.  “Experimental evidence of selection and stabilization of spatial patterns in a CO2 laser by means of spatial perturbations”

M. Ciofini, A. Labate, R. Meucci, and Peng-Ye Wang

Opt. Commun. 154, 307 (1998). [ PDF ( 793kB ) ]

  1.  “Stabilization, selection, and tracking of unstable patterns by weak spatial perturbations ”

Peng-Ye Wang, Ping Xie, Jian-Hua Dai, and Hong-Jun Zhang

Phys. Rev. Lett. 80, 4669 (1998). [ PDF ( 378kB ) ]

  1. “First-passage-time distributions of the Freedericksz transition in nematic liquid crystals”

Peng-Ye Wang

Mol. Cryst. Liq. Cryst. 319, 1 (1998). [ PDF ( 500kB ) ]

  1. “Transient statistics of the Freedericksz transition in nematic liquid crystals”

Peng-Ye Wang

Mol. Cryst. Liq. Cryst. 302, 397 (1997).

  1. “Temporal behavior and instabilities of the self-pumped phase conjugation in photorefractive crystals”

Ping Xie, Jian-Hua Dai, Peng-Ye Wang, and Hong-Jun Zhang

Phys. Rev. A. 56, 936 (1997).

  1.  “Self-pumped phase conjugation in photorefractive crystals: reflectivity and spatial fidelity”

Ping Xie, Jian-Hua Dai, Peng-Ye Wang, and Hong-Jun Zhang

Phys. Rev. A 55, 3092, (1997).

  1.  “Mechanism of self-pumped phase conjugation in photorefractive BaTiO3:Ce”

Ping Xie, Jian-Hua Dai, Peng-Ye Wang, and Hong-Jun Zhang

Appl. Phys. Lett. 69, 4005 (1996).

  1. “Bit correction and memory effects in high-speed pump modulation of a fiber laser”

J. C. Garreau, Peng-Ye Wang, and P. Glorieux

IEEE J. Quantum. Elect. 30, 1058 (1994).

  1.  “Role of population noise on the transient statitics of a CO2 laser near threshold”

M. Ciofini, R. Meucci, Peng-Ye Wang, and F. T. Arecchi

Europhys. Lett. 21, 735 (1993).

  1.  “Two-peaked passage time distributions in transient CO2 lasers near threshold”

M. Ciofini, A. Lapucci, R. Meucci, Peng-Ye Wang, and F. T. Arecchi

Phys. Rev. A 46, 5874 (1992).

  1.  “Onset of subcritical bifurcation in a CO2 laser with feedback”

Peng-Ye Wang, A. Lapucci, R. Meucci, and F. T. Arecchi

Opt. Commun. 80, 42 (1990).

  1. “Optically induced frequency locking of a nematic liquid crystal in a Fabry-Perot interferometer”

Peng-Ye Wang, Jian-Hua Dai, and Hong-Jun Zhang

Phys. Rev. A 41, 3250(1990). [ PDF ( 516kB ) ]

  1. “Laser-heating-induced self-phase modulation, phase transition, and bistability in nematic liquid crystals”

Peng-Ye Wang, Hong-Jun Zhang, and Jian-Hua Dai

Opt. Lett. 13, 479 (1988). [ PDF (440kB) ]

  1. “Feedback-induced first-order Freedericksz transition in a nematic film”

Peng-Ye Wang, Hong-Jun Zhang, and Jian-Hua Dai

Opt. Lett. 12, 654 (1987). [ PDF (455kB) ]